nStride Injections

What is nStride APS?

nStride APS (anti inflammatory protein solution) is an autologous injection therapy that is designed to alleviate pain associated with knee osteoarthritis.

How Does nStride APS Therapy Work?

The nStride APS injection treatment introduces high levels of ‘good’ proteins concentrated from your own blood. These anti-inflammatory proteins can block ‘bad’ proteins responsible for causing inflammation in the joint, which blocks cartilage destruction in osteoarthritis. Pain in the joint is reduced, resulting in improved function.

In general, the injection provides:

  • Relief from Joint pain
  • Anti-inflammatory effects
  • Improvement of joint function
  • Promotion of healthy cartilage
  • Stimulates cell proliferation
  • Decreased cartilage degeneration
  • Improved mobility
  • Delay in needing invasive surgery for up to 2 years
  • Stimulates cell proliferation

Who is Suitable for nStride APS Therapy?

The most suitable candidates for nStride APS therapy are those with mild to moderate osteoarthritis.

What Does the Treatment Involve?

nStride APS therapy is an autologous treatment, meaning ‘from your own body’. A small amount of blood is taken from the arm and then processed using a centrifuge to separate the plasma in the blood. The plasma is then processed again with a centrifuge to extract a protein liquid that is injected into the knee joint.


As nStride APS therapy is not a surgical procedure, there is no specific downtime after your treatment, although it is suggested that you minimise your levels of activity for approximately 14 days. It is recommended that you bring someone with you on the day of treatment, as you may experience local pain, bruising or swelling from where the blood was drawn.

Pain is typically reduced within 1-2 weeks and studies suggest one injection can last from 12-24 months, delaying the need for surgical joint replacements.


It is important to bear in mind that there is no cure for osteoarthritis, but successful treatment with nStride APS therapy may reduce or relieve your pain. You should also bear in mind that your osteoarthritis may not improve, and in some cases, may get worse.