Prolotherapy (Proliferative Therapy), also know as Non-Surgical Ligament and Tendon Reconstruction and Regenerative Joint Injection is an injection technique used to stimulate tissue repair in tendons and joints. Prolotherapy Injections have been used for almost 100 years. Prolotherapy injections contain natural substances that stimulate the healing response, as well as local anesthetic agents to help with the pain of the injection. Traditional formulas include ingredients such as dextrose, saline and procaine or lidocaine. It induces a mild inflammatory response which is created by the Dextrose injection, which encourages growth of new, normal ligament or tendon fibers, resulting in a tightening of the weakened structure. Additional treatments repeat this process, allowing a gradual buildup of tissue to restore the original strength to the area.